Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1994-10-13
|
| pubmed:abstractText |
Breast carcinoma is the commonest cancer in women. Segregation analyses support the existence of a major susceptibility gene with a dominant pattern of inheritance in 4 to 10% of cases. Three genes involved in the genetic predisposition to breast tumors have recently been identified: BRCA-1 associated with early onset familial breast cancer and breast/ovarian carcinoma syndrome, p53 associated with Li-Fraumeni syndrome, and the androgen receptor gene in male breast cancer with Reinfenstein syndrome. A better understanding of inherited contribution may have important implications for screening individuals at high-risk in families.
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0003-3944
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
48
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
303-8
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:8085754-Ataxia Telangiectasia,
pubmed-meshheading:8085754-Breast Neoplasms,
pubmed-meshheading:8085754-Female,
pubmed-meshheading:8085754-Genes, p53,
pubmed-meshheading:8085754-Hamartoma Syndrome, Multiple,
pubmed-meshheading:8085754-Humans,
pubmed-meshheading:8085754-Li-Fraumeni Syndrome,
pubmed-meshheading:8085754-Male,
pubmed-meshheading:8085754-Ovarian Neoplasms
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
[Genetics and cancer of the breast].
|
| pubmed:publicationType |
Editorial,
English Abstract,
Review
|