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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1994-10-13
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pubmed:abstractText |
The etiological agent of Borna disease, a persistent virus infection of the central nervous system with differently expressed symptomatology, was morphologically unknown. Here we provide the first convincing data on its phenotypic architecture. Salt-released virus comprising the biological parameters of Koch's postulates has an unsegmented single-stranded RNA. A dense band (1.22 g/cm3) in CsCl contains 90-nm particles which appear to be enveloped and a fraction of 50- to 60-nm particles. Labeling of the virions with neutralizing antisera and colloidal gold conjugates indicates that the 90-nm particles most likely represent the causative agent.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-1006279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-1454837,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-1538196,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-1693432,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-1895063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-2238474,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-2244211,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-3051132,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-3920840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-4345258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-6437125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-7905125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-7906311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8107202,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8183914,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8188810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8204140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8219797,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8237200,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8237201,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8254777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8317098,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8084008-8450648
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6755-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8084008-Animals,
pubmed-meshheading:8084008-Birds,
pubmed-meshheading:8084008-Borna disease virus,
pubmed-meshheading:8084008-Cats,
pubmed-meshheading:8084008-Cell Line,
pubmed-meshheading:8084008-Cell-Free System,
pubmed-meshheading:8084008-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8084008-Genome, Viral,
pubmed-meshheading:8084008-Horses,
pubmed-meshheading:8084008-Microscopy, Immunoelectron,
pubmed-meshheading:8084008-Oligodendroglia,
pubmed-meshheading:8084008-RNA, Viral,
pubmed-meshheading:8084008-Sheep,
pubmed-meshheading:8084008-Virion
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pubmed:year |
1994
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pubmed:articleTitle |
Borna disease virus: immunoelectron microscopic characterization of cell-free virus and further information about the genome.
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pubmed:affiliation |
Institut für Virologie, Freie Universität Berlin, Berlin, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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