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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1994-10-11
|
pubmed:abstractText |
The accuracy of DNA repair may play a role in determining the cytotoxic effect of ionizing radiation. Repair, as measured by DNA strand breakage, often shows little difference between tumor cell lines of widely different radiosensitivity. The mechanism by which DNA fragments are rejoined is poorly understood. This study used plasmid transfection as a probe to assess the balance between correct repair and misrepair.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0360-3016
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
30
|
pubmed:volume |
29
|
pubmed:geneSymbol |
gpt,
neo
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1035-40
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8083072-DNA,
pubmed-meshheading:8083072-DNA, Circular,
pubmed-meshheading:8083072-DNA Damage,
pubmed-meshheading:8083072-DNA Repair,
pubmed-meshheading:8083072-DNA Restriction Enzymes,
pubmed-meshheading:8083072-Humans,
pubmed-meshheading:8083072-Neoplasms,
pubmed-meshheading:8083072-Plasmids,
pubmed-meshheading:8083072-Radiation Tolerance,
pubmed-meshheading:8083072-Transfection,
pubmed-meshheading:8083072-Tumor Cells, Cultured
|
pubmed:year |
1994
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pubmed:articleTitle |
The repair fidelity of restriction enzyme-induced double strand breaks in plasmid DNA correlates with radioresistance in human tumor cell lines.
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pubmed:affiliation |
Radiation Research Unit, Institute of Cancer Research, Sutton, Surrey, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|