rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1994-10-10
|
pubmed:abstractText |
Murein synthesis in Escherichia coli can be partially inhibited by D-methionine without concomitant alterations in growth and morphology. D-Methionine-treated cultures grow steadily for an indefinite time, therefore murein surface density should be reduced. Determination of this parameter in control and D-methionine-treated cells showed a severe reduction in the latter. Murein surface density increases drastically in resting cells, irrespective of the presence of D-methionine. Mutants in ponB are hypersensitive to D-methionine. Analysis of ponB strains revealed an important reduction in murein surface density. An approximately two-fold reduction in average surface density is apparently compatible with normal growth and division.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0378-1097
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
121
|
pubmed:geneSymbol |
ponA,
ponB
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
71-6
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:8082828-Bacterial Proteins,
pubmed-meshheading:8082828-Carrier Proteins,
pubmed-meshheading:8082828-Cell Division,
pubmed-meshheading:8082828-Diaminopimelic Acid,
pubmed-meshheading:8082828-Escherichia coli,
pubmed-meshheading:8082828-Genetic Variation,
pubmed-meshheading:8082828-Hexosyltransferases,
pubmed-meshheading:8082828-Methionine,
pubmed-meshheading:8082828-Multienzyme Complexes,
pubmed-meshheading:8082828-Muramoylpentapeptide Carboxypeptidase,
pubmed-meshheading:8082828-Penicillin-Binding Proteins,
pubmed-meshheading:8082828-Peptidoglycan,
pubmed-meshheading:8082828-Peptidyl Transferases,
pubmed-meshheading:8082828-Stereoisomerism
|
pubmed:year |
1994
|
pubmed:articleTitle |
Variability of peptidoglycan surface density in Escherichia coli.
|
pubmed:affiliation |
Centro de Biología Molecular Severo Ochoa CSIC-UAM, Facultad de Ciencias (Biología), Madrid, Spain.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|