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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-10-11
pubmed:abstractText
In this study, the mortality of clinically treated Japanese alcoholics with diabetes mellitus was analysed. Fifty-one diabetic alcoholics without liver cirrhosis (DM), 23 diabetic and cirrhotic alcoholics (DM.LC), 44 cirrhotic alcoholics without diabetes (LC), and 354 alcoholics without either complication (AL) admitted to the National Institute on Alcoholism in 1985 were studied. Thirty-seven diabetics required insulin treatment, and 12 oral hypoglycemic agents. The 4.4-year survival and drinking status after discharge were studied in 1990. Stepwise logistic regression analysis showed that the estimated odds for death increased 8.10, 4.38, 3.70, and 3.27 times for the subjects with the alcohol misuse after discharge, DM, DM.LC, and LC, respectively. The 4.4-year survival rate of alcoholics who continued misusing alcohol was much lower in DM (26%,P < 0.0005) and LC (35%, P < 0.0001) than in AL (73%). The survival rate of those who stopped misusing alcohol was significantly higher in DM (90%, P < 0.0001), LC (88%, P < 0.0001) and AL (94%, P < 0.0005) than those who continued misusing alcohol. There was no significant difference in the survival rate between the alcoholics with DM.LC who continued misusing alcohol (50%) and those who stopped misusing alcohol (73%). In the dead patients, 56% of DM died unexpectedly or suddenly, whereas 71% of LD died of liver failure after hospitalization. These results suggest that diabetic alcoholics should be intensively educated for abstinence.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0735-0414
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
181-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The impact of diabetes mellitus on the prognosis of alcoholics.
pubmed:affiliation
National Institute on Alcoholism, Kurihama National Hospital, Kanagawa, Japan.
pubmed:publicationType
Journal Article