Linked Life Data

807966

Source:http://linkedlifedata.com/resource/pubmed/id/807966

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1975-11-6
pubmed:abstractText
IgM molecules in pure IgM preparations and in the corresponding sera from three patients with Waldenström's macroglobulinemia have been studied by analytical ultracentrifugation, rate zonal ultracentrifugation, agarose-polyacrylamide gel electrophoresis, and electron microscopy. One of the IgM preparations was without J chain, while the two others contained J chain. The experiments revealed that IgM with J chain consisted of pentameric molecules; whereas in IgM preparations without J chain the dominating molecules were hexamers, but also pentamers, tetramers, and even smaller molecules were found. In both types of IgM the molecules formed a wide range of aggregates, which were usually more abundant in the purified IgM than in serum. Some of the aggregates were kept together by noncovalent forces only.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-9475
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-28
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
IgM molecules with and without J chain in serum and after purification, studied by ultracentrifugation, electrophoresis, and electron microscopy.
pubmed:publicationType
Journal Article