rdf:type |
|
lifeskim:mentions |
umls-concept:C0006556,
umls-concept:C0017262,
umls-concept:C0033640,
umls-concept:C0033684,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0205314,
umls-concept:C0216045,
umls-concept:C0376702,
umls-concept:C0679622,
umls-concept:C1514562,
umls-concept:C1522642,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221,
umls-concept:C2700640,
umls-concept:C2911684
|
pubmed:issue |
1
|
pubmed:dateCreated |
1994-10-3
|
pubmed:databankReference |
|
pubmed:abstractText |
A full-length cDNA of human myotonin protein kinase (MtPK) was cloned and expressed in COS-1 cells. MtPK is recovered from the cytosolic fraction of the COS extract as a 70 kDa protein, which coincides with the size deduced from the predicted amino acid sequence. The sequence has a significant homology to thymopoietin, a peptide hormone of the thymus. Biochemical characteristics of MtPK expressed in COS-1 cells and its expression in rat tissues are investigated.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0014-5793
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
29
|
pubmed:volume |
351
|
pubmed:geneSymbol |
MtPK
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
22-6
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:8076686-Amino Acid Sequence,
pubmed-meshheading:8076686-Animals,
pubmed-meshheading:8076686-Base Sequence,
pubmed-meshheading:8076686-Blotting, Western,
pubmed-meshheading:8076686-Cell Line,
pubmed-meshheading:8076686-Cloning, Molecular,
pubmed-meshheading:8076686-DNA, Complementary,
pubmed-meshheading:8076686-Humans,
pubmed-meshheading:8076686-Molecular Sequence Data,
pubmed-meshheading:8076686-Protein Kinases,
pubmed-meshheading:8076686-Protein-Serine-Threonine Kinases,
pubmed-meshheading:8076686-Rats,
pubmed-meshheading:8076686-Sequence Homology, Amino Acid,
pubmed-meshheading:8076686-Thymopoietins
|
pubmed:year |
1994
|
pubmed:articleTitle |
Expression of a novel human myotonin protein kinase (MtPK) cDNA clone which encodes a protein with a thymopoietin-like domain in COS cells.
|
pubmed:affiliation |
Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|