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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1994-10-4
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pubmed:databankReference |
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pubmed:abstractText |
Pertussis toxin is an exotoxin of the A-B class produced by Bordetella pertussis. The holotoxin comprises 952 residues forming six subunits (five different sequences, S1-S5). It plays an important role in the development of protective immunity to whooping cough, and is an essential component of new acellular vaccines. It is also widely used as a biochemical tool to ADP-ribosylate GTP-binding proteins in the study of signal transduction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0969-2126
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-57
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8075982-Amino Acid Sequence,
pubmed-meshheading:8075982-Bordetella pertussis,
pubmed-meshheading:8075982-Computer Graphics,
pubmed-meshheading:8075982-Crystallography, X-Ray,
pubmed-meshheading:8075982-Macromolecular Substances,
pubmed-meshheading:8075982-Models, Molecular,
pubmed-meshheading:8075982-Molecular Sequence Data,
pubmed-meshheading:8075982-Pertussis Toxin,
pubmed-meshheading:8075982-Protein Structure, Secondary,
pubmed-meshheading:8075982-Sequence Homology, Amino Acid,
pubmed-meshheading:8075982-Synchrotrons,
pubmed-meshheading:8075982-Virulence Factors, Bordetella,
pubmed-meshheading:8075982-X-Ray Diffraction
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pubmed:year |
1994
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pubmed:articleTitle |
The crystal structure of pertussis toxin.
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pubmed:affiliation |
Department of Medical Microbiology and Infectious Diseases, University of Alberta, Edmonton, Canada.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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