Linked Life Data

8074792

Source:http://linkedlifedata.com/resource/pubmed/id/8074792

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-4
pubmed:dateCreated
1994-10-4
pubmed:abstractText
Golgi-Cox impregnated loci of the thalamic reticular nucleus (TRN) of normal and neonatally T4-treated Wistar strain rats at 12, 20 and 30 days of age were analyzed. In a total of 120 TRN camera lucida drawings. The number of visible neurons, the area and the maximal transverse TRN length were quantitated. T4-treated rats showed a significant increase in the number of neurons at 12 days of age, followed by significant reductions of this parameter at 20 and 30 days old. By contrast the area of TRN hyperthyroid rats showed significant reductions on days 20 and 30 postnatally, and the maximal transverse length of the same group of rats showed a consistent significant reduction only at 30 days postpartum. The data are partly in line with previous studies showing an initial accelerated brain maturation, followed by a subsequent neuronal retardation, although the area and the maximal transverse TRN length measurements did not exhibit this sequence of development. The findings suggest that neonatal T4-treatment may interfere with the TRN morphological organization, and the modulatory actions upon the thalamic sensory transmission.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0067-9666
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-7
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:articleTitle
Alterations in the thalamic reticular nucleus of rats neonatally treated with thyroxine.
pubmed:affiliation
Department of Physiology, Universidad Nacional Autónoma de México, D. F. México.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't