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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1994-9-29
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pubmed:abstractText |
Psychiatric disorders have been reported in over 10% of patients with velo-cardio-facial syndrome (VCFS) in long-term follow-up. To further explore the behavioral and psychiatric findings associated with VCFS in adulthood, detailed clinical histories of two patients--one with VCFS who developed a psychotic illness, and one with schizophrenia who was found to have dysmorphological features associated with VCFS--are described in the current report. The observed overlap of physical and psychiatric symptoms in these two patients suggests that VCFS and psychotic disorders may share a pathogenetic mechanism. This could be consistent with a contiguous gene model for VCFS and psychosis, suggesting chromosome 22q11 as a possible candidate region for genetic studies of schizophrenia.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-1308357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-1349369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-1360769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-272242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-3597719,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-3606332,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-3619396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-3816857,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-3995791,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-4019731,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-4044789,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-5696314,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-6736220,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-7243439,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-8230155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-8322039,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-8434616,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8074160-8434617
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0148-7299
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-12
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pubmed:dateRevised |
2011-8-1
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pubmed:meshHeading |
pubmed-meshheading:8074160-Abnormalities, Multiple,
pubmed-meshheading:8074160-Adult,
pubmed-meshheading:8074160-Chromosomes, Human, Pair 22,
pubmed-meshheading:8074160-Face,
pubmed-meshheading:8074160-Female,
pubmed-meshheading:8074160-Genetics, Behavioral,
pubmed-meshheading:8074160-Heart Defects, Congenital,
pubmed-meshheading:8074160-Humans,
pubmed-meshheading:8074160-Male,
pubmed-meshheading:8074160-Psychotic Disorders,
pubmed-meshheading:8074160-Syndrome
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pubmed:year |
1994
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pubmed:articleTitle |
Velo-cardio-facial syndrome and psychotic disorders: implications for psychiatric genetics.
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pubmed:affiliation |
Department of Psychiatry, Queen Street Mental Health Centre, Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Case Reports
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