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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1994-9-23
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pubmed:abstractText |
Interleukin-1-beta (IL-1-beta), Interleukin-6 (IL-6) and Interferon-gamma (IFN-gamma) were measured by enzyme immunoassay (EIA) methods in blister fluids (BFs) obtained from both involved (ISBF) and non-involved skin (USBF) and in sera from 14 psoriatic patients. The same determinations were carried out in 14 sera and in 5 suction blister fluids from 14 normal subjects. IL-6 was always detectable in all skin fluids and in 3 psoriasis sera. IL-1-beta was measured only in 5 ISBFs and in 5 sera from the same patients. IFN-gamma was present in 11 ISBFs, in 5 USBFs and in 5 sera. The analysis of the levels found in the samples shows: 1) a local production of these cytokines, 2) the presence of detectable amounts of IL-6 and IFN-gamma in USBFs, and 3) a significant correlation between the IL-6 levels in the ISBFs and erythema score.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0365-8341
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
186
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
23-4
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8073828-Adolescent,
pubmed-meshheading:8073828-Adult,
pubmed-meshheading:8073828-Aged,
pubmed-meshheading:8073828-Blister,
pubmed-meshheading:8073828-Exudates and Transudates,
pubmed-meshheading:8073828-Female,
pubmed-meshheading:8073828-Humans,
pubmed-meshheading:8073828-Immunoenzyme Techniques,
pubmed-meshheading:8073828-Interferon-gamma,
pubmed-meshheading:8073828-Interleukin-1,
pubmed-meshheading:8073828-Interleukin-6,
pubmed-meshheading:8073828-Male,
pubmed-meshheading:8073828-Middle Aged,
pubmed-meshheading:8073828-Psoriasis,
pubmed-meshheading:8073828-Sensitivity and Specificity,
pubmed-meshheading:8073828-Skin
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pubmed:year |
1994
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pubmed:articleTitle |
Interleukin-1-beta, interleukin-6, and interferon-gamma in suction blister fluids of involved and uninolved skin and in sera of psoriatic patients.
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pubmed:affiliation |
Third Department of Dermatology, S. Gallicano Institute, Rome, Italy.
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pubmed:publicationType |
Journal Article
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