Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1994-9-27
pubmed:abstractText
Within the scope of evaluating transparent oil-water gels (TOW gel) as dermatological vehicles, the release of indomethacin from a model TOW gel into 1-dodecanol is studied at various pH levels of the water phase. Apparent partition coefficient determinations and flame photometrical measurements show that both indomethacin and its sodium salt, as the ion pair, migrate into the 1-dodecanol layer. The pH-dependent release-rate profile is explained in terms of the amount of readily diffusible drug in the water phase of the gel.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-3549
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
641-3
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Release of indomethacin from transparent oil-water gels.
pubmed:affiliation
Laboratory of Galenical and Clinical Pharmacy, Catholic University of Leuven, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't