Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1994-9-29
|
| pubmed:abstractText |
A direct antiglobulin test (DAT) was performed in 70 patients with anti-HIV antibodies (group A: seropositive patients without or with minimal disease and group B: AIDS patients with or without malignancies). A positive DAT was found in 24 of 70 patients (34%, significantly higher compared to 0.1% in healthy controls) and a higher prevalence of positive DAT was observed in group B than in group A patients (55% versus 21% p < 0.01). When comparing DAT-positive and negative patients within the same clinical group, no significant difference is seen in haemoglobin levels. There is no difference in serum bilirubin, haptoglobin or reticulocyte count between DAT-positive and negative patients altogether or in the same clinical group. AZT therapy seems to exert no significant influence on the onset of a positive DAT. The results confirm a high prevalence of positive DAT in patients with HIV antibodies, mainly in worse clinical conditions, and suggest that a positive DAT might be a prognostic factor in the clinical course of the disease.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0300-8126
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
92-5
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8070936-Adult,
pubmed-meshheading:8070936-Anemia, Hemolytic,
pubmed-meshheading:8070936-Bilirubin,
pubmed-meshheading:8070936-CD4-CD8 Ratio,
pubmed-meshheading:8070936-Case-Control Studies,
pubmed-meshheading:8070936-Coombs' Test,
pubmed-meshheading:8070936-Female,
pubmed-meshheading:8070936-HIV Antibodies,
pubmed-meshheading:8070936-HIV Infections,
pubmed-meshheading:8070936-Haptoglobins,
pubmed-meshheading:8070936-Hematocrit,
pubmed-meshheading:8070936-Hemoglobins,
pubmed-meshheading:8070936-Humans,
pubmed-meshheading:8070936-Male,
pubmed-meshheading:8070936-Middle Aged,
pubmed-meshheading:8070936-Prevalence,
pubmed-meshheading:8070936-Prognosis,
pubmed-meshheading:8070936-Reticulocyte Count,
pubmed-meshheading:8070936-Risk Factors,
pubmed-meshheading:8070936-Severity of Illness Index
|
| pubmed:articleTitle |
Clinical significance of positive direct antiglobulin test in patients with HIV infection.
|
| pubmed:affiliation |
Servizio Immunotrasfusionale e Analisi Cliniche, I.R.C.C.S. Centro di Riferimento Oncologico, Aviano, Italy.
|
| pubmed:publicationType |
Journal Article
|