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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1994-9-29
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pubmed:databankReference | |
pubmed:abstractText |
Core I protein is the largest subunit of ubiquinol-cytochrome c reductase. We have isolated a complete cDNA clone of 1575 bp encoding the precursor to this protein by screening a human fibroblast cDNA library. Nucleotide sequence comparison showed that the human core I protein cDNA is about 85% homologous with the reported bovine counter part but with a large difference in the length of coding region which consists of 480 amino acids in human and 362 amino acids in bovine. Human core I protein is presumed to contain a presequence of 34 amino acids. Amino acid sequence alignment study showed that the predicted human core I protein has a significant homology with other members of matrix processing peptidase (MPP) and processing enhancing protein (PEP) family.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1039-9712
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
797-805
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8069229-Amino Acid Sequence,
pubmed-meshheading:8069229-Animals,
pubmed-meshheading:8069229-Base Sequence,
pubmed-meshheading:8069229-Cattle,
pubmed-meshheading:8069229-Cloning, Molecular,
pubmed-meshheading:8069229-DNA, Complementary,
pubmed-meshheading:8069229-DNA Probes,
pubmed-meshheading:8069229-Electron Transport Complex III,
pubmed-meshheading:8069229-Gene Expression Regulation,
pubmed-meshheading:8069229-Gene Library,
pubmed-meshheading:8069229-Genetic Code,
pubmed-meshheading:8069229-Humans,
pubmed-meshheading:8069229-Molecular Sequence Data,
pubmed-meshheading:8069229-Peptide Fragments,
pubmed-meshheading:8069229-Polymerase Chain Reaction,
pubmed-meshheading:8069229-Sequence Alignment,
pubmed-meshheading:8069229-Sequence Homology, Amino Acid
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pubmed:year |
1994
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pubmed:articleTitle |
A complete cDNA sequence for core I protein subunit of human ubiquinol-cytochrome c reductase.
|
pubmed:affiliation |
Department of Biomedical Chemistry, Faculty of Medicine, University of Nagoya, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|