Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1994-9-22
pubmed:abstractText
The total intra-individual variation of fasting urinary calcium- and hydroxyproline-creatinine ratios were determined both as outpatients and as inpatients in 46 patients with metabolic bone disorders, including 20 women with osteoporosis. The intra-individual variation of both measurements was reduced considerably by collecting samples in the ward rather than in the outpatient setting, although this was not the case for a sub-group of osteoporotic women. The large intra-individual variation observed for calcium and hydroxyproline (30-40% in osteoporotic women) can give rise to misclassification in screening for fast bone losers. The very large critical difference required (109% and 94%, respectively, for calcium and hydroxyproline) for two results to reflect a significant change, is a major limitation in the use of these analytes for monitoring bone resorption in menopausal and osteoporotic women.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0004-5632
pubmed:author
pubmed:issnType
Print
pubmed:volume
31 ( Pt 3)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
272-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Intra-individual variation in fasting urinary calcium- and hydroxyproline-creatinine ratios measured in metabolic bone clinic patients as both outpatients and inpatients.
pubmed:affiliation
WHO Collaborating Centre for Metabolic Bone Disease, University of Sheffield Medical School, UK.
pubmed:publicationType
Journal Article