Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1994-9-22
|
pubmed:abstractText |
The total intra-individual variation of fasting urinary calcium- and hydroxyproline-creatinine ratios were determined both as outpatients and as inpatients in 46 patients with metabolic bone disorders, including 20 women with osteoporosis. The intra-individual variation of both measurements was reduced considerably by collecting samples in the ward rather than in the outpatient setting, although this was not the case for a sub-group of osteoporotic women. The large intra-individual variation observed for calcium and hydroxyproline (30-40% in osteoporotic women) can give rise to misclassification in screening for fast bone losers. The very large critical difference required (109% and 94%, respectively, for calcium and hydroxyproline) for two results to reflect a significant change, is a major limitation in the use of these analytes for monitoring bone resorption in menopausal and osteoporotic women.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0004-5632
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
31 ( Pt 3)
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
272-6
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8067669-Aged,
pubmed-meshheading:8067669-Aged, 80 and over,
pubmed-meshheading:8067669-Bone Diseases, Metabolic,
pubmed-meshheading:8067669-Calcium,
pubmed-meshheading:8067669-Creatinine,
pubmed-meshheading:8067669-Fasting,
pubmed-meshheading:8067669-Female,
pubmed-meshheading:8067669-Humans,
pubmed-meshheading:8067669-Hydroxyproline,
pubmed-meshheading:8067669-Inpatients,
pubmed-meshheading:8067669-Male,
pubmed-meshheading:8067669-Middle Aged,
pubmed-meshheading:8067669-Outpatients,
pubmed-meshheading:8067669-Reproducibility of Results
|
pubmed:year |
1994
|
pubmed:articleTitle |
Intra-individual variation in fasting urinary calcium- and hydroxyproline-creatinine ratios measured in metabolic bone clinic patients as both outpatients and inpatients.
|
pubmed:affiliation |
WHO Collaborating Centre for Metabolic Bone Disease, University of Sheffield Medical School, UK.
|
pubmed:publicationType |
Journal Article
|