Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1994-9-19
pubmed:databankReference
pubmed:abstractText
Mutation in the REC2 gene of Ustilago maydis leads to defects in DNA repair, recombination, and meiosis. Analysis of the primary sequence of the Rec2 protein reveals a region with significant homology to bacterial RecA protein and to the yeast recombination proteins Dmc1, Rad51, and Rad57. This homologous region in the U. maydis Rec2 protein was found to be functionally sensitive to mutation, lending support to the hypothesis that Rec2 has a functional RecA-like domain essential for activity in recombination and repair. Homologous recombination between plasmid and chromosomal DNA sequences is reduced substantially in the rec2 mutant following transformation. The frequency can be restored to a level approaching, but not exceeding, that observed in the wild-type strain if transformation is performed with cells containing multiple copies of REC2.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1001898, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1105573, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1152859, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1581960, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1581961, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1620127, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1620128, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1648366, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1731246, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1783291, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1883888, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-1937004, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2041810, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2269439, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2292186, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2323553, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2470512, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2628171, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2660904, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2667641, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2744487, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2779577, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2829206, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2851726, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2922262, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-2936601, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-3022939, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-3050531, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-3162770, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-3273407, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-3474623, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-5878282, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-6059022, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-6235151, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-6312838, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-6329717, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-6330525, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-6694911, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-7439684, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-8276878, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-8371266, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-8419331, http://linkedlifedata.com/resource/pubmed/commentcorrection/8065360-8456313
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0270-7306
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6287-96
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Structure of REC2, a recombinational repair gene of Ustilago maydis, and its function in homologous recombination between plasmid and chromosomal sequences.
pubmed:affiliation
Department of Microbiology, Cornell University Medical College, New York, New York 10021.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.