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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0023693,
umls-concept:C0034121,
umls-concept:C0034929,
umls-concept:C0085801,
umls-concept:C0205307,
umls-concept:C0549193,
umls-concept:C0681850,
umls-concept:C0728938,
umls-concept:C1261322,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C1707520,
umls-concept:C2349001,
umls-concept:C2349099,
umls-concept:C2697811
|
| pubmed:issue |
4
|
| pubmed:dateCreated |
1994-9-22
|
| pubmed:abstractText |
Pupillary test data of 103 normal and 119 diabetic subjects (47 IDDM, 72 NIDDM) were evaluated by factor analysis. From a total of nine pupillary parameters three factors were extracted in the analysis. Factor 1 represents maximal pupillary area, contraction velocity at 1 s, dilation velocity at 6 s and minimal pupillary area--static and simple dynamic parameters; factor 2 amplitude of pupillary unrest, area under the detrended curve of pupillary unrest and period of pupillary unrest--parameters of pupillary unrest; factor 3 fusion frequency of pupillary response following flicker stimuli and latency time of pupillary light reflex--second order dynamic parameters. Factor analysis was then applied to investigate diabetic patients with a high percentage of autonomic neuropathic participants (about 39% had pupillary and about 35% had cardiorespiratory function disorders), which revealed the same three factors as those identified in normal subjects. Furthermore, an age-related database of parameters of pupillary unrest is given. It demonstrates that normal subjects and diabetic patients did not differ in the period of pupillary unrest (normal vs diabetic (mean +/- SEM): 1550 +/- 29 vs 1536 +/- 27 ms; 2p > 0.5). The difference in amplitude (47.8 +/- 2.8 vs 41.0 +/- 2.6% percentile; 2p = 0.071) and area under the detrended curve of pupillary unrest (47.9 +/- 2.8 vs 40.8 +/- 2.6% percentile, 2p = 0.062) seems to show a trend but was not significant. In conclusion, factor analysis revealed three different pupillary test factors.(ABSTRACT TRUNCATED AT 250 WORDS)
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0012-186X
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
37
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
414-9
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| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8063044-Adolescent,
pubmed-meshheading:8063044-Adult,
pubmed-meshheading:8063044-Aged,
pubmed-meshheading:8063044-Aged, 80 and over,
pubmed-meshheading:8063044-Autonomic Nervous System Diseases,
pubmed-meshheading:8063044-Diabetes Mellitus, Type 1,
pubmed-meshheading:8063044-Diabetes Mellitus, Type 2,
pubmed-meshheading:8063044-Factor Analysis, Statistical,
pubmed-meshheading:8063044-Female,
pubmed-meshheading:8063044-Humans,
pubmed-meshheading:8063044-Light,
pubmed-meshheading:8063044-Male,
pubmed-meshheading:8063044-Middle Aged,
pubmed-meshheading:8063044-Pupil,
pubmed-meshheading:8063044-Reflex, Pupillary
|
| pubmed:year |
1994
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| pubmed:articleTitle |
Valid parameters for investigation of the pupillary light reflex in normal and diabetic subjects shown by factor analysis and partial correlation.
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| pubmed:affiliation |
Department of Internal Medicine I, University Hospital, Regensburg, Germany.
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| pubmed:publicationType |
Journal Article
|