| pubmed-article:8061219 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8061219 | lifeskim:mentions | umls-concept:C0005767 | lld:lifeskim |
| pubmed-article:8061219 | lifeskim:mentions | umls-concept:C0205093 | lld:lifeskim |
| pubmed-article:8061219 | lifeskim:mentions | umls-concept:C0005528 | lld:lifeskim |
| pubmed-article:8061219 | lifeskim:mentions | umls-concept:C0013878 | lld:lifeskim |
| pubmed-article:8061219 | lifeskim:mentions | umls-concept:C0038960 | lld:lifeskim |
| pubmed-article:8061219 | lifeskim:mentions | umls-concept:C0205374 | lld:lifeskim |
| pubmed-article:8061219 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8061219 | pubmed:dateCreated | 1994-9-21 | lld:pubmed |
| pubmed-article:8061219 | pubmed:abstractText | Concentration profiles of 2.5 microns latex beads were measured to demonstrate lateral transport of platelet-sized objects in flows of blood suspensions; the flows had equivalent Poiseuille wall shear rates (WSRs) from 250 to 1220 s-1. Each experimental trial began with a steady flow of suspension without beads in a thin-walled capillary tube (219 microns ID; 10.2 microns SD). The tube entrance was then switched to a reservoir containing suspension of equal hematocrit, but with beads, for a short interval of flow at the same WSR. This process established a paraboloidal tongue of labeled suspension with a transient concentration gradient at its surface. The tube and contents were rapidly frozen to fix the suspended particles in flow-determined locations. Segments of frozen tube were collected at distances from the entrance corresponding to 13%, 39%, and 65% of the axial extent of the ideal paraboloidal tongue. Concentration profiles were estimated from distances measured on fluorescence microscope images of cross-cut tube segments. Experiments used tubes either 40 or 50 cm long, suspension hematocrits of 0, 15, or 40%, and bead concentrations in the range of 1.5-2.2 x 10(5)/mm3. Profiles for 0% hematocrit suspension, a dilute, single-component suspension, had features expected in normal diffusive mixing in a flow. Distinctly different profiles and more lateral transport occurred when the suspensions contained red cells; then, all profiles for 13% extent had regions of excess bead concentration near the wall. Suspension flows with 40% hematocrit exhibited the largest amount of lateral transport. A case is made that, to a first approximation, the rate of lateral transport grew linearly with WSR; however, statistical analysis showed that for 40% hematocrit, less lateral transport occurred when the WSR was 250 s-1 or 1220 s-1 than 560 s-1, thus indicating that the rate behavior is more complex. | lld:pubmed |
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| pubmed-article:8061219 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8061219 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8061219 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8061219 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8061219 | pubmed:month | May | lld:pubmed |
| pubmed-article:8061219 | pubmed:issn | 0006-3495 | lld:pubmed |
| pubmed-article:8061219 | pubmed:author | pubmed-author:EcksteinE CEC | lld:pubmed |
| pubmed-article:8061219 | pubmed:author | pubmed-author:YehCC | lld:pubmed |
| pubmed-article:8061219 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8061219 | pubmed:volume | 66 | lld:pubmed |
| pubmed-article:8061219 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8061219 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8061219 | pubmed:pagination | 1706-16 | lld:pubmed |
| pubmed-article:8061219 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:8061219 | pubmed:meshHeading | pubmed-meshheading:8061219-... | lld:pubmed |
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| pubmed-article:8061219 | pubmed:meshHeading | pubmed-meshheading:8061219-... | lld:pubmed |
| pubmed-article:8061219 | pubmed:meshHeading | pubmed-meshheading:8061219-... | lld:pubmed |
| pubmed-article:8061219 | pubmed:meshHeading | pubmed-meshheading:8061219-... | lld:pubmed |
| pubmed-article:8061219 | pubmed:meshHeading | pubmed-meshheading:8061219-... | lld:pubmed |
| pubmed-article:8061219 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8061219 | pubmed:articleTitle | Transient lateral transport of platelet-sized particles in flowing blood suspensions. | lld:pubmed |
| pubmed-article:8061219 | pubmed:affiliation | Department of Biomedical Engineering, University of Miami, Florida. | lld:pubmed |
| pubmed-article:8061219 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8061219 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:8061219 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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