Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1994-9-20
pubmed:abstractText
Cerebellar ataxia with hypogonadotropic hypogonadism is a rare condition. Both hypothalamic LHRH and pituitary gonadotropin deficiency may appear with cerebellar ataxia. In this report, a 19-year-old man who presented with progressive cerebellar ataxia and mental disturbance was found to have low plasma gonadotropin levels. No rise in gonadotropin was demonstrated after repeated stimulation with LHRH. Our findings suggested that the cause of hypogonadism was pituitary gonadotropin deficiency, or both hypothalamic and pituitary dysfunction. The endocrinological data and clinical features of our patient and all other reported cases suggest that the age of onset of the illness is related to the type of endocrinological abnormality: young-onset patients may have endocrine disturbances involving both the hypothalamus and the pituitary gland, which may be affected secondary to the hypothalamic disturbance, whereas adult-onset patients may show only hypothalamic disturbance.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-8969
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
493-6
pubmed:dateRevised
2007-2-22
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[Cerebellar ataxia with hypogonadotropic hypogonadism and mental disturbance].
pubmed:affiliation
Department of Neurology, Urafune Hospital, Yokohama City University School of Medicine, Japan.
pubmed:publicationType
Journal Article, English Abstract, Review, Case Reports