Linked Life Data

8059412

Source:http://linkedlifedata.com/resource/pubmed/id/8059412

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1994-9-15
pubmed:abstractText
The data are available on concentrations of Willebrand factor antigen (FVIII Ag) in 43 patients with rheumatoid arthritis (RA), 19 patients with livedo vasculitis (LV) and 56 donors. The measurements were made with solid-phase enzyme immunoassay. RA patients were found to display significantly higher concentrations of FVIII Ag (1.88 +/- 0.17 IU/ml) versus donors (1.06 +/- 0.05 IU/ml, p < 0.001) and LV patients (1.08 +/- 0.09 IU/ml, p < 0.001). No significant differences existed between FVIII Ag concentrations in LV patients and donors (p > 0.05). In 12 (28%) out of 43 RA patients FVIII Ag levels rose to 3 standard deviations from the mean in donors. Hyperproduction of FVIII Ag was associated with skin vasculitis symptoms in RA patients (p = 0.0004), more frequent occurrence of antinuclear factor (p = 0.02). Elevated concentrations of FVIII Ag did not relate to other extraarticular RA symptoms and general rheumatic inflammation, X-ray stage, RF titer, cryoglobulins, enhanced ESR, C-reactive protein.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0040-3660
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-72
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[The von Willebrand factor antigen in patients with rheumatoid arthritis: a method for its determination and the clinical significance].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract