Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1975-9-9
pubmed:abstractText
Evidence of a local immunologic response to recent pharyngeal infection with group A streptococci was sought in 23 patients with acute rheumatic fever. Salivas from these patients were examined and compared with salivas from control subjects. As assayed, both IgG and IgA values ranged between 8 and 170 mg. per 100 ml. in 10-fold concentrated samples of saliva. When these values were corrected for the concentration of the samples and for the use of serum IgA standards, the following mean values were obtained: for patients with acute rheumatic fever, IgG was 4.5 mg. per 100 ml. and IgA was 8.7 mg. per 100 ml.; for control subjects, IgG was 5.0 mg per 100 ml. and IgA was 9.9 mg. per 100 ml. IgM was present in amounts of 1 to 2 mg. per 100 ml. in 2 patients and 7 control subjects. Antistreptolysin O titers correlated with amounts of IgG in the saliva samples while antihyaluronidase, antigroup A carbohydrate, and antiteichoic acid titers did not. None of the antibody titers correlated with the IgA content of the saliva samples. Furthermore, saliva antibody titers did not differ between patients with acute rheumatic fever and control subjects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-2143
pubmed:author
pubmed:issnType
Print
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1013-21
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:805815-Acute Disease, pubmed-meshheading:805815-Adolescent, pubmed-meshheading:805815-Adult, pubmed-meshheading:805815-Age Factors, pubmed-meshheading:805815-Antibodies, Bacterial, pubmed-meshheading:805815-Antistreptolysin, pubmed-meshheading:805815-Child, pubmed-meshheading:805815-Child, Preschool, pubmed-meshheading:805815-Clinical Trials as Topic, pubmed-meshheading:805815-Female, pubmed-meshheading:805815-Humans, pubmed-meshheading:805815-Immunodiffusion, pubmed-meshheading:805815-Immunoglobulin A, pubmed-meshheading:805815-Immunoglobulin G, pubmed-meshheading:805815-Immunoglobulin M, pubmed-meshheading:805815-Male, pubmed-meshheading:805815-Rheumatic Fever, pubmed-meshheading:805815-Saliva, pubmed-meshheading:805815-Sex Factors, pubmed-meshheading:805815-Streptococcus
pubmed:year
1975
pubmed:articleTitle
Salivary immunoglobulins and streptococcal antibodies in patients with acute rheumatic fever.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S.