Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1994-9-13
pubmed:abstractText
The aim of this study was to find out the influence of radiofrequency (RF) capacitive heating on the alpha 1-adrenergic receptor of rat prostates. The prostates of 30-week-old Wistar rats were submitted to a 1-hour single session of RF capacitive heating at 45 degrees C. The ventral prostates that were submitted to heating were compared to those of other rats that were not submitted to heating. In order to determine the density of alpha 1-adrenergic receptors in rat ventral prostates, binding assays for alpha 1-adrenergic receptor were performed with [3H]prazosin in membrane preparations. The receptor density in the control group was 27.07 +/- 3.75 fmol/mg protein. The alpha 1-adrenergic receptor density (Bmax) in the thermotherapy group was 17.91 +/- 5.15 fmol/mg protein. A remarkable decrease in the density of alpha 1-adrenergic receptors was observed in the rat prostates of the thermotherapy group. In conclusion, the present results demonstrate that heating the rat prostate by RF capacitive heating damages the alpha 1-adrenergic receptors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0302-2838
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
330-3
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Influence of RF capacitive heating on the alpha 1-adrenergic receptors of rat prostates.
pubmed:affiliation
Department of Urology, Kanazawa Medical University, Ishikawa, Japan.
pubmed:publicationType
Journal Article