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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1975-7-23
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pubmed:abstractText |
A short treatment with ethylenedinitrilotetraacetic acid to permeabilize bacteria for various antibiotics or treatment with the ribonucleic acid (RNA) synthesis inhibitor rifampin causes a slow degradation of 50S and 30S ribosomal particles and of the corresponding 23S and 16S ribosomal RNA species (about 25 percent in 1 h). The effects are additive such that the decay is about 50 percent/h if rifampin is employed after permeabilization by ethylenedinitrilotetraacetic acid. The 5S ribosomal RNA and transfer RNA are essentially stable under these conditions.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-14265747,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4197337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4203109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4337104,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4562111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4573848,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4576589,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4586982,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4600702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4602396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4890765,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4938545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4938556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4940987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-4967191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-5001420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/805122-6035921
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
122
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
425-32
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:805122-Drug Stability,
pubmed-meshheading:805122-Edetic Acid,
pubmed-meshheading:805122-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:805122-Escherichia coli,
pubmed-meshheading:805122-Nucleic Acid Denaturation,
pubmed-meshheading:805122-RNA, Bacterial,
pubmed-meshheading:805122-RNA, Ribosomal,
pubmed-meshheading:805122-RNA, Transfer,
pubmed-meshheading:805122-Ribosomes,
pubmed-meshheading:805122-Rifampin
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pubmed:year |
1975
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pubmed:articleTitle |
Stability of ribosomal and transfer ribonucleic acid in Escherichia coli B/r after treatment with ethylenedinitrilotetraacetic acid and rifampicin.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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