Linked Life Data

8050622

Source:http://linkedlifedata.com/resource/pubmed/id/8050622

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1994-9-8
pubmed:abstractText
This paper compiles the clinical behavioral phenomenology of individuals with autistic spectrum disorder (ASD) with a family history of bipolar affective disorder (BPAD) or major depression and no identified neurological disorder, based on repeated clinical interviews during extended follow-up (ranging from six months to 21 (mean 3.9) years. Their pattern of affective and cognitive symptoms showed notable similarities across the entire group, despite wide variations in severity; was congruent with standard definitions of ASD; showed many features of childhood BPAD, including affective extremes, cyclicity, obsessive traits, special abilities, and regression after initial normal development; and differed from that of autistic children with neurological etiologies. These observations support the concept that ASD in some cases may be etiologically related to BPAD.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0012-1622
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
674-87
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Children with autistic spectrum disorder and a family history of affective disorder.
pubmed:affiliation
Department of Pediatrics, Duke University Medical Center, Durham, NC 27710.
pubmed:publicationType
Journal Article, Comparative Study, Case Reports, Research Support, Non-U.S. Gov't