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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1994-9-6
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pubmed:abstractText |
Two ubiquitous (L- and F-type) and one muscle-specific (M-type) mRNA species are generated by the human aldolase A gene. Despite the high degree of sequence similarities in the promoter region between human and rodents, no L-type mRNA expression has yet been found in the latter. Here we demonstrate that L-type aldolase A mRNA is expressed during the differentiation of mouse myogenic C2.7 and rat oligodendrocyte precursor CEINGE C13 cells. The L-type mRNA expression is increased during differentiation and is associated with cell-growth arrest caused by nocodazole treatment or serum deprivation in C2.7 and CEINGE C13 cells, respectively. The L-type aldolase A mRNA is correctly processed at the L1-L2 junction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0014-4827
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
213
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
359-64
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8050493-Animals,
pubmed-meshheading:8050493-Base Sequence,
pubmed-meshheading:8050493-Cell Differentiation,
pubmed-meshheading:8050493-Cell Division,
pubmed-meshheading:8050493-Cell Line,
pubmed-meshheading:8050493-Culture Media, Serum-Free,
pubmed-meshheading:8050493-DNA,
pubmed-meshheading:8050493-Exons,
pubmed-meshheading:8050493-Fructose-Bisphosphate Aldolase,
pubmed-meshheading:8050493-Humans,
pubmed-meshheading:8050493-Introns,
pubmed-meshheading:8050493-Isoenzymes,
pubmed-meshheading:8050493-Mice,
pubmed-meshheading:8050493-Molecular Sequence Data,
pubmed-meshheading:8050493-Nocodazole,
pubmed-meshheading:8050493-Promoter Regions, Genetic,
pubmed-meshheading:8050493-RNA, Messenger,
pubmed-meshheading:8050493-Rats,
pubmed-meshheading:8050493-Transcription, Genetic
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pubmed:year |
1994
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pubmed:articleTitle |
Growth-arrested dependence of aldolase A L-type mRNA expression in rodent cell lines.
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pubmed:affiliation |
Dipartimento Biochimica e Biotecnologie Mediche, Facoltà di Medicina, Università degli studi di Napoli Federico II.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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