Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1994-9-7
|
| pubmed:abstractText |
Retrospective analysis was made of office and hospital records of patients with sickle cell hemoglobinopathies. Blood products were transfused only when indicated for symptomatic anemia, severe anemia with a hematocrit less than 18%, sickle crisis, cardiovascular instability, and preoperatively. The Fisher exact test and the Student t test were used for statistical analysis; P < 0.05 was considered significant. All mean values are reported +/- 1 standard deviation. From 1981 to 1991, 40 patients with sickle cell hemoglobinopathies had a total of 61 singleton pregnancies: 36 were complicated by SS disease (SSD), 22 by sickle cell disease (SCD), two by sickle-thalassemia, and one had CC disease (CCD). Only patients with SSD and SCD are reported here. The mean maternal age was 24.3 +/- 5.3 and 19.5 +/- 0.6 years in patients with SSD and SCD, respectively. There was a high occurrence of preterm labor (45% and 20%), preeclampsia (20% and 8.7%), pain crisis (50% and 34.2%), pulmonary complications (25% and 16.7%), and cesarean sections (52.6% and 37.1%) in SSD and SCD, respectively. An average of two units of blood was required by 43.1% of the patients. Two patients with SSD had unpreventable deaths. The mean gestational age at delivery was 35.5 +/- 4.3 and 37.0 +/- 3.7 weeks (P < 0.05), and the mean birthweight was 2443 +/- 926 and 2997 +/- 807 g (P < 0.05), respectively. There were two intrauterine fetal deaths and one neonatal death in the SSD group and one neonatal death in the SCD group. The perinatal mortality was 10.5% and 2.9%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0735-1631
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
11
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
187-91
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8048982-Adult,
pubmed-meshheading:8048982-Anemia, Sickle Cell,
pubmed-meshheading:8048982-Birth Weight,
pubmed-meshheading:8048982-Blood Transfusion,
pubmed-meshheading:8048982-Female,
pubmed-meshheading:8048982-Gestational Age,
pubmed-meshheading:8048982-Hemoglobin SC Disease,
pubmed-meshheading:8048982-Humans,
pubmed-meshheading:8048982-Maternal Age,
pubmed-meshheading:8048982-Pregnancy,
pubmed-meshheading:8048982-Pregnancy Complications, Hematologic,
pubmed-meshheading:8048982-Pregnancy Outcome,
pubmed-meshheading:8048982-Retrospective Studies
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Outcome of pregnancies complicated by sickle cell and sickle-C hemoglobinopathies.
|
| pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City.
|
| pubmed:publicationType |
Journal Article
|