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rdf:type |
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lifeskim:mentions |
umls-concept:C0006556,
umls-concept:C0007371,
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0022567,
umls-concept:C0086418,
umls-concept:C0162326,
umls-concept:C0205409,
umls-concept:C0936012,
umls-concept:C1171362,
umls-concept:C1515670
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pubmed:issue |
2
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|
pubmed:dateCreated |
1994-9-1
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|
pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29018,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29019,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29020,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29021,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29022,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29023,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29024,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29025,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29026,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29027,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29028,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29029,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29030,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29031,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29032,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29033,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29034,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29035,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29036,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29037,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29038,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29039,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29040,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29041,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29042,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29043,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29044,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29045,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29046,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/D29047
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pubmed:abstractText |
The partial nucleotide sequences of 607 cDNAs randomly isolated from a cDNA library of cultured human epidermal keratinocytes were determined by single pass sequencing. Homology search of the sequences to the non-redundant nucleotide databases revealed that 27% of the cDNAs matched registered human-or non-human genes encoding not only keratinocyte specific genes, but also a variety of functional proteins, the expression of which had not been identified in keratinocytes. Non-matching cDNAs covering 49% of the cDNAs were not homologous even to ESTs from other organs, suggesting that these cDNAs include novel genes expressed in the cells. The large scale sequencing of keratinocyte cDNAs provides a useful molecular source for research into biology and diseases of the skin.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0006-291X
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
29
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pubmed:volume |
202
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
976-83
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8048971-Animals,
pubmed-meshheading:8048971-Cells, Cultured,
pubmed-meshheading:8048971-DNA, Complementary,
pubmed-meshheading:8048971-Databases, Factual,
pubmed-meshheading:8048971-Gene Expression,
pubmed-meshheading:8048971-Gene Library,
pubmed-meshheading:8048971-Humans,
pubmed-meshheading:8048971-Keratinocytes,
pubmed-meshheading:8048971-Molecular Sequence Data,
pubmed-meshheading:8048971-Sequence Analysis, DNA,
pubmed-meshheading:8048971-Sequence Homology, Nucleic Acid,
pubmed-meshheading:8048971-Tissue Distribution
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pubmed:year |
1994
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|
pubmed:articleTitle |
Cataloging of the genes expressed in human keratinocytes: analysis of 607 randomly isolated cDNA sequences.
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|
pubmed:affiliation |
Department of Dermatology, Kyoto Prefectural University of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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