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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1994-9-1
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pubmed:abstractText |
The cytogenetic results from a series of 113 thyroid hyperplasias and adenomas are reported; 15 showed clonal karyotypic alterations. In addition to a group showing translocations involving 19q13, another subset of lesions characterized by polysomies can be found. Based on our own cases belonging to this subset and a review of the cases reported in the literature, we conclude that the characteristic feature of this group is a sequence that always starts with trisomy 7, but that sometimes even leads to chromosome numbers in the hypertriploid range. This subset of thyroid tumors may be an example of a more common genetic pathway in human solid tumors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0340-6717
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
198-202
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8045569-Adult,
pubmed-meshheading:8045569-Aged,
pubmed-meshheading:8045569-Chromosome Aberrations,
pubmed-meshheading:8045569-Chromosomes, Human, Pair 7,
pubmed-meshheading:8045569-Female,
pubmed-meshheading:8045569-Humans,
pubmed-meshheading:8045569-Karyotyping,
pubmed-meshheading:8045569-Male,
pubmed-meshheading:8045569-Middle Aged,
pubmed-meshheading:8045569-Thyroid Neoplasms,
pubmed-meshheading:8045569-Trisomy
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pubmed:year |
1994
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pubmed:articleTitle |
A characteristic sequence of trisomies starting with trisomy 7 in benign thyroid tumors.
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pubmed:affiliation |
Zentrum für Humangenetik und genetische Beratung, Universität Bremen, Germany.
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pubmed:publicationType |
Journal Article
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