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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1994-8-31
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pubmed:databankReference |
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pubmed:abstractText |
A Xenopus total ovary cDNA library was constructed in a fission yeast expression vector. Using a genetic functional complementation method, we have identified a Xenopus cDNA clone that can rescue several different yeast mitotic catastrophe mutants defective in Wee1 kinase function at the restrictive temperature. The 3.0-kb cDNA clone contains an open reading frame (ORF) of 2226 nucleotides, encoding a predicted 82-kDa protein. The deduced amino acid (aa) sequence shows seven almost identical 30-aa tandem repeats, each of which contains a phosphorylation site meeting the consensus for both Cdc2 kinase and MAP kinase.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CDC2 Protein Kinase,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Schizosaccharomyces pombe Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Wee1A protein, Xenopus,
http://linkedlifedata.com/resource/pubmed/chemical/Xenopus Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/wee1 protein, S pombe
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0378-1119
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
22
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
155-6
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:8045419-Amino Acid Sequence,
pubmed-meshheading:8045419-Animals,
pubmed-meshheading:8045419-Base Sequence,
pubmed-meshheading:8045419-CDC2 Protein Kinase,
pubmed-meshheading:8045419-Cell Cycle Proteins,
pubmed-meshheading:8045419-Cloning, Molecular,
pubmed-meshheading:8045419-DNA,
pubmed-meshheading:8045419-DNA, Complementary,
pubmed-meshheading:8045419-Female,
pubmed-meshheading:8045419-Mitosis,
pubmed-meshheading:8045419-Molecular Sequence Data,
pubmed-meshheading:8045419-Nuclear Proteins,
pubmed-meshheading:8045419-Ovary,
pubmed-meshheading:8045419-Protein Kinases,
pubmed-meshheading:8045419-Protein-Tyrosine Kinases,
pubmed-meshheading:8045419-Proteins,
pubmed-meshheading:8045419-Schizosaccharomyces,
pubmed-meshheading:8045419-Schizosaccharomyces pombe Proteins,
pubmed-meshheading:8045419-Xenopus,
pubmed-meshheading:8045419-Xenopus Proteins
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pubmed:year |
1994
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pubmed:articleTitle |
Identification of a Xenopus cDNA that prevents mitotic catastrophe in the fission yeast Schizosaccharomyces pombe.
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pubmed:affiliation |
Howard Hughes Medical Institute, University of Colorado School of Medicine, Denver 80262.
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pubmed:publicationType |
Journal Article
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