rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1994-8-26
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pubmed:abstractText |
Brief episodes of ischemia render the heart more resistant to subsequent ischemia; this phenomenon has been called ischemic preconditioning. In some animal species, myocardial preconditioning appears to be due to activation of ATP-sensitive K+ (KATP) channels. The role played by KATP channels in preconditioning in humans remains unknown. The aim of this study was to establish whether glibenclamide, a selective KATP channel blocker, abolishes the ischemic preconditioning observed in humans during coronary angioplasty following repeated balloon inflations.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
pubmed:issn |
0009-7322
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
90
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
700-5
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:8044938-Adenosine Triphosphate,
pubmed-meshheading:8044938-Angioplasty, Balloon, Coronary,
pubmed-meshheading:8044938-Blood Glucose,
pubmed-meshheading:8044938-Calcium Channel Blockers,
pubmed-meshheading:8044938-Calcium Channels,
pubmed-meshheading:8044938-Coronary Circulation,
pubmed-meshheading:8044938-Electrocardiography,
pubmed-meshheading:8044938-Female,
pubmed-meshheading:8044938-Glyburide,
pubmed-meshheading:8044938-Humans,
pubmed-meshheading:8044938-Male,
pubmed-meshheading:8044938-Middle Aged,
pubmed-meshheading:8044938-Monitoring, Physiologic,
pubmed-meshheading:8044938-Myocardial Ischemia,
pubmed-meshheading:8044938-Single-Blind Method
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pubmed:year |
1994
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pubmed:articleTitle |
Ischemic preconditioning during coronary angioplasty is prevented by glibenclamide, a selective ATP-sensitive K+ channel blocker.
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pubmed:affiliation |
Servizio Speciale di Diagnosi e Cura di Emodinamica, Università di Roma Tor Vergata, European Hospital, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|