Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-8-30
pubmed:abstractText
Seemingly minor blue-toe lesions resulting from atheroemboli are associated with unstable atherosclerotic plaques, which are at risk for causing recurrent emboli, tissue loss, and potentially death. At Washington University Medical Center, 62 patients (31 males and 31 females), ranging in age from 38 to 89 years (mean 62.8 +/- 11.7 years), were treated for cutaneous manifestations of atheroembolic disease. Most patients (62%) had spontaneous bouts of atheroembolism, but 13 (21%) had recently undergone an inciting invasive radiologic study, 10 (16%) were on anticoagulation therapy, and one (2%) experienced abdominal trauma. In addition to the cutaneous manifestations, 18 patients (29%) also developed coincidental deterioration in renal function and four (6%) had intestinal infarction from atheroemboli. Arteriography in nearly all patients (97%) implicated the aorta and iliac arteries most commonly (80%), with the femoral (13%), popliteal (3%), and subclavian (3%) arteries less frequently incriminated. Forty-two patients underwent bypass grafting procedures (36 anatomic and six extra-anatomic) after exclusion of the native diseased artery, 20 patients had endarterectomies (six with additional bypass grafts), and five patients had no corrective vascular procedures. The 30-day operative mortality rate was 5% in this series. Nineteen patients (31%) required minor amputations, whereas two required major leg amputations. Thus limb salvage was possible in 86 of 88 (98%) limbs. No further episodes of atheroembolism occurred in the involved limbs during follow-up (1 to 53 months, mean 20.2 months). We advocate urgent arteriography and surgical correction or bypass with exclusion of the offending lesion.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0890-5096
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
258-65
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:8043359-Adult, pubmed-meshheading:8043359-Aged, pubmed-meshheading:8043359-Aged, 80 and over, pubmed-meshheading:8043359-Amputation, pubmed-meshheading:8043359-Angiography, pubmed-meshheading:8043359-Aortic Diseases, pubmed-meshheading:8043359-Arteriosclerosis, pubmed-meshheading:8043359-Embolism, Cholesterol, pubmed-meshheading:8043359-Endarterectomy, pubmed-meshheading:8043359-Female, pubmed-meshheading:8043359-Follow-Up Studies, pubmed-meshheading:8043359-Humans, pubmed-meshheading:8043359-Iliac Artery, pubmed-meshheading:8043359-Infarction, pubmed-meshheading:8043359-Intestinal Diseases, pubmed-meshheading:8043359-Intestines, pubmed-meshheading:8043359-Kidney Diseases, pubmed-meshheading:8043359-Male, pubmed-meshheading:8043359-Middle Aged, pubmed-meshheading:8043359-Missouri, pubmed-meshheading:8043359-Skin Diseases, Vascular, pubmed-meshheading:8043359-Survival Rate
pubmed:year
1994
pubmed:articleTitle
An institutional experience with arterial atheroembolism.
pubmed:affiliation
Department of Surgery, Washington University School of Medicine, St. Louis, Mo.
pubmed:publicationType
Journal Article