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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1994-8-23
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pubmed:abstractText |
Studies on radiation-induced changes in gene expression are likely to be very important in developing a better understanding of cellular responses to ionizing radiation. While there is some information on the activation of cellular signal transduction pathways after radiation, few late reacting target genes have been identified. This study focuses on the characterization of expression modulation of two critical growth regulatory genes, estrogen receptor and epidermal growth factor-receptor in malignant mammary epithelial cells in response to single and repeated ionizing radiation exposures.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0360-3016
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
813-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:8040028-Breast Neoplasms,
pubmed-meshheading:8040028-Cell Cycle,
pubmed-meshheading:8040028-Cell Survival,
pubmed-meshheading:8040028-Dose-Response Relationship, Radiation,
pubmed-meshheading:8040028-Gene Expression,
pubmed-meshheading:8040028-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:8040028-Humans,
pubmed-meshheading:8040028-Phenotype,
pubmed-meshheading:8040028-RNA, Messenger,
pubmed-meshheading:8040028-Receptor, Epidermal Growth Factor,
pubmed-meshheading:8040028-Receptors, Estrogen,
pubmed-meshheading:8040028-Transforming Growth Factor alpha,
pubmed-meshheading:8040028-Tumor Cells, Cultured,
pubmed-meshheading:8040028-Up-Regulation
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pubmed:year |
1994
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pubmed:articleTitle |
Altered expression of epidermal growth factor receptor and estrogen receptor in MCF-7 cells after single and repeated radiation exposures.
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pubmed:affiliation |
Department of Radiation Oncology, Medical College of Virginia, Richmond.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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