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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6 Suppl 2
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pubmed:dateCreated |
1994-8-23
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pubmed:abstractText |
Bleeding and thrombosis are frequent complications in patients with chronic myeloproliferative disorders (cMPD). Antiplatelet therapy is extensively used by many physicians for primary prophylaxis of thrombotic events, even though there have been no prospective trials that demonstrate clinical benefit. The use of aspirin has been associated with a heavy incidence of serious hemorrhages, particularly of gastrointestinal origin. This evidence is mainly based on data from patients treated with dosages far higher than those presently recommended. Moreover, patients with bleeding symptoms or prolonged bleeding time (BT) had not usually been excluded from treatment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0390-6078
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
18-21
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8039753-Adult,
pubmed-meshheading:8039753-Aged,
pubmed-meshheading:8039753-Aged, 80 and over,
pubmed-meshheading:8039753-Aspirin,
pubmed-meshheading:8039753-Bleeding Time,
pubmed-meshheading:8039753-Female,
pubmed-meshheading:8039753-Follow-Up Studies,
pubmed-meshheading:8039753-Gastrointestinal Hemorrhage,
pubmed-meshheading:8039753-Hemorrhage,
pubmed-meshheading:8039753-Humans,
pubmed-meshheading:8039753-Incidence,
pubmed-meshheading:8039753-Leukopenia,
pubmed-meshheading:8039753-Male,
pubmed-meshheading:8039753-Middle Aged,
pubmed-meshheading:8039753-Myeloproliferative Disorders,
pubmed-meshheading:8039753-Prospective Studies,
pubmed-meshheading:8039753-Safety,
pubmed-meshheading:8039753-Stomach Diseases,
pubmed-meshheading:8039753-Thromboembolism,
pubmed-meshheading:8039753-Ticlopidine
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pubmed:articleTitle |
Is ticlopidine a safe alternative to aspirin for management of myeloproliferative disorders?
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pubmed:affiliation |
Department of Hematology, San Bortolo Hospital, Vicenza, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study
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