Linked Life Data

8038754

Source:http://linkedlifedata.com/resource/pubmed/id/8038754

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-8-19
pubmed:abstractText
Morphometric analyses were made of medial-intimal cross-sectional area and lumen diameter in transverse sections of large arteries and small arterioles from normal and deoxycorticosterone acetate-salt hypertensive animals whose vasculatures were perfusion fixed at their in vivo mean arterial pressures. During the borderline and established phases of hypertension, changes in medial cross sectional area and lumen diameter were not detected in any vessel. During chronic mineralocorticoid hypertension, significant (p < 0.05) medial hypertrophy and an increased lumen diameter were found in the abdominal aorta whereas these parameters were normal in other large conduits, small arteries, and arterioles examined. These results indicate that medial hypertrophy is a late consequence of chronic hypertension in this model and is confined primarily to the abdominal aorta. Further, remodelling without medial hypertrophy may explain the normal lumen diameters of small arteries and arterioles in this model of hypertension.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1064-1963
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-82
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Smooth muscle hypertrophy and arterial remodelling in deoxycorticosterone acetate-salt hypertension.
pubmed:affiliation
Department of Physiology, University of Maryland, Baltimore 21201.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't