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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1994-8-17
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pubmed:abstractText |
Two hundred and eighty patients with stigmata of recent or active bleeding from a peptic ulcer were followed up after endoscopic or conservative medical treatment. Of the patients 53% had no history of dyspeptic symptoms, but 17% and 10% had a history of uncomplicated ulcer or bleeding ulcer, respectively, before the index admission. After 8 years of follow-up the estimated recurrence rate was 29% (95% confidence limits, 12-47%). At recurrence 65% of the patients presented with a rebleed and 12% with a perforation. By means of a logistic regression analysis, a previous history of ulcer haemorrhage was identified as the only predictor associated with a significantly increased risk of recurrence. The recurrence rate in 253 patients presenting with a first bleed at the index admission was 23%, compared with 73% in 27 patients with a history of bleeding before the index admission (p = 0.001). The rate of recurrence was not influenced by a history of previous uncomplicated ulcer disease or dyspeptic symptoms, the severity of the index bleed, the methods of management of the index bleed, age, use of non-steroidal anti-inflammatory drugs, or long-term treatment with cimetidine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0036-5521
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
414-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8036456-Adult,
pubmed-meshheading:8036456-Aged,
pubmed-meshheading:8036456-Aged, 80 and over,
pubmed-meshheading:8036456-Dyspepsia,
pubmed-meshheading:8036456-Female,
pubmed-meshheading:8036456-Follow-Up Studies,
pubmed-meshheading:8036456-Humans,
pubmed-meshheading:8036456-Male,
pubmed-meshheading:8036456-Middle Aged,
pubmed-meshheading:8036456-Peptic Ulcer Hemorrhage,
pubmed-meshheading:8036456-Peptic Ulcer Perforation,
pubmed-meshheading:8036456-Recurrence,
pubmed-meshheading:8036456-Regression Analysis
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pubmed:year |
1994
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pubmed:articleTitle |
Peptic ulcer hemorrhage: factors predisposing to recurrence.
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pubmed:affiliation |
Dept. of Surgical Gastroenterology, Aarhus Kommunehospital, Denmark.
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pubmed:publicationType |
Journal Article
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