| pubmed-article:8034744 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8034744 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
| pubmed-article:8034744 | lifeskim:mentions | umls-concept:C0025979 | lld:lifeskim |
| pubmed-article:8034744 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:8034744 | lifeskim:mentions | umls-concept:C0200765 | lld:lifeskim |
| pubmed-article:8034744 | lifeskim:mentions | umls-concept:C0597705 | lld:lifeskim |
| pubmed-article:8034744 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:8034744 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8034744 | pubmed:dateCreated | 1994-8-12 | lld:pubmed |
| pubmed-article:8034744 | pubmed:abstractText | The three-dimensional structure of actin filaments decorated with the actin-binding domain of chick smooth muscle alpha-actinin (alpha A1-2) has been determined to 21-A resolution. The shape and location of alpha A1-2 was determined by subtracting maps of F-actin from the reconstruction of decorated filaments. alpha A1-2 resembles a bell that measures approximately 38 A at its base and extends 42 A from its base to its tip. In decorated filaments, the base of alpha A1-2 is centered about the outer face of subdomain 2 of actin and contacts subdomain 1 of two neighboring monomers along the long-pitch (two-start) helical strands. Using the atomic model of F-actin (Lorenz, M., D. Popp, and K. C. Holmes. 1993. J. Mol. Biol. 234:826-836.), we have been able to test directly the likelihood that specific actin residues, which have been previously identified by others, interact with alpha A1-2. Our results indicate that residues 86-117 and 350-375 comprise distinct binding sites for alpha-actinin on adjacent actin monomers. | lld:pubmed |
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| pubmed-article:8034744 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8034744 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8034744 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8034744 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8034744 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8034744 | pubmed:issn | 0021-9525 | lld:pubmed |
| pubmed-article:8034744 | pubmed:author | pubmed-author:WayMM | lld:pubmed |
| pubmed-article:8034744 | pubmed:author | pubmed-author:DeRosierDD | lld:pubmed |
| pubmed-article:8034744 | pubmed:author | pubmed-author:McGoughAA | lld:pubmed |
| pubmed-article:8034744 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8034744 | pubmed:volume | 126 | lld:pubmed |
| pubmed-article:8034744 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8034744 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8034744 | pubmed:pagination | 433-43 | lld:pubmed |
| pubmed-article:8034744 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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