Cryoelectron Microscopy

Source:http://linkedlifedata.com/resource/umls/id/C0597705

CSP: three-dimensional image reconstruction technique whereby an aqueous suspension of a sample is applied in an extremely thin film to a grid, frozen in liquid nitrogen, maintained in this state by means of a special mount, and then observed in the electron microscope.,MSH: Electron microscopy involving rapid freezing of the samples. The imaging of frozen-hydrated molecules and organelles permits the best possible resolution closest to the living state, free of chemical fixatives or stains.,NCI: Electron microscopy involving an aqueous suspension of a sample which is applied in an extremely thin film to a grid, frozen in liquid nitrogen and maintained in this state by means of a special mount. The imaging of frozen-hydrated molecules and organelles permits the best possible resolution closest to the living state, free of chemical fixatives or stains.

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