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pubmed-article:8026747pubmed:abstractTextA partial cDNA clone encoding a putative nicotinic acetylcholine receptor (ACHR) subunit of the human filarial parasite, Onchocerca volvulus, has been isolated and sequenced. A truncated open reading frame of 1308 bp capable of encoding 436 amino acids with a calculated M(r) of 51,209 was identified. The absence of the double cysteine residues necessary for neurotransmitter binding indicates that the cloned ACHR is a non-alpha subunit.lld:pubmed
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pubmed-article:8026747pubmed:articleTitleCloning of a cDNA encoding a putative nicotinic acetylcholine receptor subunit of the human filarial parasite Onchocerca volvulus.lld:pubmed
pubmed-article:8026747pubmed:affiliationDepartment of Filarial Molecular Biology, Centre International de Recherches Médicales de Franceville, Gabon.lld:pubmed
pubmed-article:8026747pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8026747pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed