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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1994-8-5
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pubmed:databankReference | |
pubmed:abstractText |
A partial cDNA clone encoding a putative nicotinic acetylcholine receptor (ACHR) subunit of the human filarial parasite, Onchocerca volvulus, has been isolated and sequenced. A truncated open reading frame of 1308 bp capable of encoding 436 amino acids with a calculated M(r) of 51,209 was identified. The absence of the double cysteine residues necessary for neurotransmitter binding indicates that the cloned ACHR is a non-alpha subunit.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0378-1119
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
144
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8026747-Amino Acid Sequence,
pubmed-meshheading:8026747-Animals,
pubmed-meshheading:8026747-Base Sequence,
pubmed-meshheading:8026747-Cloning, Molecular,
pubmed-meshheading:8026747-DNA, Complementary,
pubmed-meshheading:8026747-Humans,
pubmed-meshheading:8026747-Molecular Sequence Data,
pubmed-meshheading:8026747-Onchocerca volvulus,
pubmed-meshheading:8026747-Receptors, Nicotinic,
pubmed-meshheading:8026747-Sequence Homology, Amino Acid
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pubmed:year |
1994
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pubmed:articleTitle |
Cloning of a cDNA encoding a putative nicotinic acetylcholine receptor subunit of the human filarial parasite Onchocerca volvulus.
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pubmed:affiliation |
Department of Filarial Molecular Biology, Centre International de Recherches Médicales de Franceville, Gabon.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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