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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-7-29
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pubmed:abstractText |
Human herpesvirus 7 (HHV-7) was isolated from peripheral blood mononuclear cells of two infants with typical exanthem subitum. The HindIII-, BamHI-, and EcoRI-digested DNA patterns of the isolated viruses were very similar to that of the prototype HHV-7 (RK strain), but different from that of human herpesvirus 6 (HHV-6). During the convalescent period of the first patient, the titer of antibody to HHV-7 rose from < 1:10 to 1:320 by an immunofluorescence antibody test, whereas the titer of antibody to HHV-6 remained < 1:10. In the second patient, who had two independent episodes of exanthem subitum during 2 months, both HHV-6 and HHV-7 were sequentially isolated; seroconversion to HHV-6 occurred during the first episode and to HHV-7 during the second episode. In addition, sera from another 15 children who had episodes of exanthem subitum were serologically tested for antibodies to HHV-6 and HHV-7 by immunofluorescence antibody test. Five of seven patients had seroconversion to HHV-7 just after having typical signs and symptoms of exanthem subitum. These results suggest that HHV-7 is one of the causative agents of exanthem subitum.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-3476
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8021757-Child, Preschool,
pubmed-meshheading:8021757-Exanthema Subitum,
pubmed-meshheading:8021757-Female,
pubmed-meshheading:8021757-Herpesviridae Infections,
pubmed-meshheading:8021757-Herpesvirus 6, Human,
pubmed-meshheading:8021757-Herpesvirus 7, Human,
pubmed-meshheading:8021757-Humans,
pubmed-meshheading:8021757-Infant,
pubmed-meshheading:8021757-Male,
pubmed-meshheading:8021757-Serotyping
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pubmed:year |
1994
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pubmed:articleTitle |
Human herpesvirus 7: another causal agent for roseola (exanthem subitum).
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pubmed:affiliation |
Department of Pediatrics, Osaka University Medical School, Japan.
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pubmed:publicationType |
Journal Article
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