rdf:type |
|
lifeskim:mentions |
umls-concept:C0002874,
umls-concept:C0005961,
umls-concept:C0017649,
umls-concept:C0018129,
umls-concept:C0021079,
umls-concept:C0021080,
umls-concept:C0024230,
umls-concept:C0205341,
umls-concept:C0332152,
umls-concept:C0439810,
umls-concept:C0939276
|
pubmed:issue |
1
|
pubmed:dateCreated |
1994-7-29
|
pubmed:abstractText |
Allogeneic BMT for severe aplastic anemia is associated with a significant rate of graft rejection, especially in patients who have been previously transfused. We report a child with aplastic anemia who rejected donor marrow twice despite adequate immunosuppression as part of the conditioning therapy but engrafted successfully following combined administration of three modalities of immunosuppression: antithymocyte globulin, total lymphoid irradiation and the monoclonal antibody Campath-1G. Restriction fragment length polymorphism studies > 1 year after BMT show full donor hematopoiesis with no evidence of autologous recovery.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Antilymphocyte Serum,
http://linkedlifedata.com/resource/pubmed/chemical/CD52 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Tetracycline,
http://linkedlifedata.com/resource/pubmed/chemical/alemtuzumab
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0268-3369
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
13
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
97-9
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8019459-Anemia, Aplastic,
pubmed-meshheading:8019459-Antibodies, Monoclonal,
pubmed-meshheading:8019459-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:8019459-Antibodies, Neoplasm,
pubmed-meshheading:8019459-Antigens, CD,
pubmed-meshheading:8019459-Antigens, Neoplasm,
pubmed-meshheading:8019459-Antilymphocyte Serum,
pubmed-meshheading:8019459-Bone Marrow Transplantation,
pubmed-meshheading:8019459-Child, Preschool,
pubmed-meshheading:8019459-Glycoproteins,
pubmed-meshheading:8019459-Graft Rejection,
pubmed-meshheading:8019459-Humans,
pubmed-meshheading:8019459-Immunosuppression,
pubmed-meshheading:8019459-Lymphoid Tissue,
pubmed-meshheading:8019459-Male,
pubmed-meshheading:8019459-Reoperation,
pubmed-meshheading:8019459-Tetracycline
|
pubmed:year |
1994
|
pubmed:articleTitle |
Total lymphoid irradiation, anti-lymphocyte globulin and Campath 1-G for immunosuppression prior to bone marrow transplantation for aplastic anemia after repeated graft rejection.
|
pubmed:affiliation |
Department of Bone Marrow Transplantation, Hadassah University Hospital, Jerusalem, Israel.
|
pubmed:publicationType |
Journal Article,
Case Reports
|