Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1994-8-4
|
pubmed:abstractText |
General pulse sequence elements that achieve sensitivity-enhanced coherence transfer from a heteronucleus to protons of arbitrary multiplicity are introduced. The building blocks are derived from the sensitivity-enhancement scheme introduced by Cavanagh et al. ((1991) J. Magn. Reson., 91, 429-436), which was used in conjunction with gradient coherence selection by Kay et al. ((1992) J. Am. Chem. Soc., 114, 10663-10665), as well as from a multiple-pulse sequence effecting a heteronuclear planar coupling Hamiltonian. The building blocks are incorporated into heteronuclear correlation experiments, in conjunction with coherence selection by the formation of a heteronuclear gradient echo. This allows for efficient water suppression without the need for water presaturation. The methods are demonstrated in HSQC-type experiments on a sample of a decapeptide in H2O. The novel pulse sequence elements can be incorporated into multidimensional experiments.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0925-2738
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
301-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8019138-Amino Acid Sequence,
pubmed-meshheading:8019138-Gonadotropin-Releasing Hormone,
pubmed-meshheading:8019138-Indicators and Reagents,
pubmed-meshheading:8019138-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8019138-Mathematics,
pubmed-meshheading:8019138-Molecular Sequence Data,
pubmed-meshheading:8019138-Oligopeptides,
pubmed-meshheading:8019138-Protein Conformation,
pubmed-meshheading:8019138-Sensitivity and Specificity
|
pubmed:year |
1994
|
pubmed:articleTitle |
A general enhancement scheme in heteronuclear multidimensional NMR employing pulsed field gradients.
|
pubmed:affiliation |
Institut für Organische Chemie, Universität Frankfurt, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|