Linked Life Data

8018947

Source:http://linkedlifedata.com/resource/pubmed/id/8018947

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-8-4
pubmed:abstractText
The etiology of Burkitt's lymphoma (BL) includes three factors which operate in a stepwise fashion: (1) the ubiquitous Epstein-Barr virus (EBV) which possesses oncogenic potential when it infects infants or very young children; (2) malaria which specifically depresses cytotoxic T cell clones controlling the polyclonal proliferation of EBV-infected B cells in the host; and (3) chromosomal translocations activating the c-myc oncogene which in turn induces uncontrolled B cell proliferation. The unravelling of such a multistep carcinogenic process has shaken a number of well-established dogmas of our time.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0340-4684
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:geneSymbol
c-myc
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
667-73; discussion 674-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
The etiology of Burkitt's lymphoma and the history of the shaken dogmas.
pubmed:affiliation
Unité d'Epidémiologie des Virus Oncogènes, Institut Pasteur, Paris, France.
pubmed:publicationType
Journal Article, Comparative Study, Review