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rdf:type |
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lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0005847,
umls-concept:C0007578,
umls-concept:C0017262,
umls-concept:C0026473,
umls-concept:C0034493,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0225336,
umls-concept:C0333348,
umls-concept:C1515655,
umls-concept:C2911684
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|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1994-7-28
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|
pubmed:abstractText |
Monocyte adhesion to the vascular endothelium, an important component of an inflammatory response, is one of the earliest detected events in the pathogenesis of atherosclerosis. We have identified a monocyte adhesion molecule, recognized by monoclonal antibody (mAb) IG9, on the cell surface of human umbilical vein endothelial cells (HUVEC) treated with tumor necrosis factor-alpha (TNF-alpha), interleukin-1, or lipopolysaccharide. Endothelial cell expression in vitro and in vivo of the protein recognized by mAb IG9 (IG9 protein) was further characterized.
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pubmed:grant |
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pubmed:language |
eng
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|
pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
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|
pubmed:issn |
0023-6837
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
836-49
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8015288-Animals,
pubmed-meshheading:8015288-Antibodies, Monoclonal,
pubmed-meshheading:8015288-Aorta,
pubmed-meshheading:8015288-Arteriosclerosis,
pubmed-meshheading:8015288-Cell Adhesion,
pubmed-meshheading:8015288-Cell Adhesion Molecules,
pubmed-meshheading:8015288-Cell Line,
pubmed-meshheading:8015288-Cell Membrane,
pubmed-meshheading:8015288-Cells, Cultured,
pubmed-meshheading:8015288-Coronary Vessels,
pubmed-meshheading:8015288-Endothelium, Vascular,
pubmed-meshheading:8015288-Humans,
pubmed-meshheading:8015288-Immunohistochemistry,
pubmed-meshheading:8015288-Inflammation,
pubmed-meshheading:8015288-Leukemia, Promyelocytic, Acute,
pubmed-meshheading:8015288-Lung,
pubmed-meshheading:8015288-Monocytes,
pubmed-meshheading:8015288-Muscle, Smooth, Vascular,
pubmed-meshheading:8015288-Myocardium,
pubmed-meshheading:8015288-Rabbits,
pubmed-meshheading:8015288-Tumor Cells, Cultured,
pubmed-meshheading:8015288-Tumor Necrosis Factor-alpha,
pubmed-meshheading:8015288-Umbilical Veins
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|
pubmed:year |
1994
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|
pubmed:articleTitle |
An endothelial cell adhesion protein for monocytes recognized by monoclonal antibody IG9. Expression in vivo in inflamed human vessels and atherosclerotic human and Watanabe rabbit vessels.
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pubmed:affiliation |
Department of Pathology, Albert Einstein College of Medicine, Bronx, New York.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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