| pubmed-article:8012930 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8012930 | lifeskim:mentions | umls-concept:C1564874 | lld:lifeskim |
| pubmed-article:8012930 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8012930 | lifeskim:mentions | umls-concept:C0087140 | lld:lifeskim |
| pubmed-article:8012930 | lifeskim:mentions | umls-concept:C0013081 | lld:lifeskim |
| pubmed-article:8012930 | lifeskim:mentions | umls-concept:C0079070 | lld:lifeskim |
| pubmed-article:8012930 | lifeskim:mentions | umls-concept:C0086860 | lld:lifeskim |
| pubmed-article:8012930 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8012930 | pubmed:dateCreated | 1994-7-25 | lld:pubmed |
| pubmed-article:8012930 | pubmed:abstractText | Adeno-associated virus (AAV) is a non-pathogenic human parvovirus which has anti-tumor and anti-proliferation properties in tissue culture and animal studies. Furthermore, AAV infection is negatively associated with human cervical cancer. C-myc has been implicated in cervical cancer, and c-fos is involved in signal transduction initiation of cell growth. To study the potential regulation of these two prominent human proto-oncogenes by AAV, the expression of three marker coding sequences ligated 3' of the proto-oncogene promoters were observed. Demonstrated here, the AAV Rep78 gene product was able to down-regulate the human c-fos and c-myc proto-oncogene promoters in all three assay systems. These interactions may partially explain AAVs anti-proliferation properties. | lld:pubmed |
| pubmed-article:8012930 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8012930 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8012930 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8012930 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8012930 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8012930 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8012930 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8012930 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8012930 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:8012930 | pubmed:issn | 0304-3835 | lld:pubmed |
| pubmed-article:8012930 | pubmed:author | pubmed-author:HermonatP LPL | lld:pubmed |
| pubmed-article:8012930 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8012930 | pubmed:day | 30 | lld:pubmed |
| pubmed-article:8012930 | pubmed:volume | 81 | lld:pubmed |
| pubmed-article:8012930 | pubmed:geneSymbol | c-fos | lld:pubmed |
| pubmed-article:8012930 | pubmed:geneSymbol | c-myc | lld:pubmed |
| pubmed-article:8012930 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8012930 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8012930 | pubmed:pagination | 129-36 | lld:pubmed |
| pubmed-article:8012930 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
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| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
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| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:meshHeading | pubmed-meshheading:8012930-... | lld:pubmed |
| pubmed-article:8012930 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8012930 | pubmed:articleTitle | Down-regulation of the human c-fos and c-myc proto-oncogene promoters by adeno-associated virus Rep78. | lld:pubmed |
| pubmed-article:8012930 | pubmed:affiliation | University of Arkansas for Medical Sciences, Department of Obstetrics and Gynecology, Little Rock 72205. | lld:pubmed |
| pubmed-article:8012930 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8012930 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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