Linked Life Data

8012490

Source:http://linkedlifedata.com/resource/pubmed/id/8012490

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-7-25
pubmed:abstractText
The expression of Fc-gamma-R (FcR) classes on circulating leucocyte lineages (lymphocytes, monocytes, granulocytes) was determined by flow cytometry in 46 fetuses at 18-35 weeks of gestation and in 11 full-term neonates, and compared to that in 20 adults. Classes of FcR present on adult leucocytes could be detected on the corresponding fetal cells as early as 18 weeks of pregnancy. Generally, in the fetus, FcR expression was lower than in the adult while in the neonate it approached values found later in life. However, percentages of Fc-gamma-RIII-positive fetal/new-born monocytes, and those of FcR-positive new-born granulocytes were considerably raised above adult levels. The modified pattern of FcR expression on fetal/new-born leucocytes is likely to influence their IgG-mediated effector activities towards targets such as red cells and platelets.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0958-7578
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-33
pubmed:dateRevised
2008-7-31
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The expression of IgG Fc receptors on circulating leucocytes in the fetus and new-born.
pubmed:affiliation
Department of Haematology, St Mary's Hospital Medical School, Imperial College of Science, Technology and Medicine, London, U.K.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't