| pubmed-article:8011678 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C0227525 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C0015684 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C0031676 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C0733755 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C1521991 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C1705920 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C1979885 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:8011678 | lifeskim:mentions | umls-concept:C1710236 | lld:lifeskim |
| pubmed-article:8011678 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8011678 | pubmed:dateCreated | 1994-7-25 | lld:pubmed |
| pubmed-article:8011678 | pubmed:abstractText | The simultaneous incorporation of a saturated fatty acid in the sn-1 position and an unsaturated fatty acid in the sn-2 position in phosphatidylcholine (PC) and ethanolamine (PE) was studied in isolated liver cells. We combined a saturated fatty acid, 16:0 or 18:0 and an unsaturated fatty acid substrate, 18:2,n-6 or 20:4,n-6. In this situation the saturated fatty acids were preferentially oxidized and the unsaturated fatty acids were preferentially esterified in PL and TG. Addition of unlabelled 16:0 increased the incorporation of [14C]18:2 in 16:0-18:2 in PC and PE, reduced the incorporation in 18:2-18:2 but did not reduce the incorporation in 18:0-18:2. 18:0 increased the esterification of [14C]18:2 in 18:0-18:2, reduced the incorporation in 18:2-18:2 but did not reduce the incorporation in 16:0-18:2. The latter is the dominating 14C-labelled species formed from [14C]18:2 also in the presence of unlabelled 18:0. Addition of 20:4 stimulated the incorporation of [14C]16:0 in 16:0-20:4 and markedly reduced the formation of 16:0-18:2, 16:0-18:1 and 16:0-22:6. Addition of 18:2 increased the incorporation of [14C]16:0 in 16:0-18:2 and reduced the formation of 16:0-20:4 and 16:0-18:1. It is concluded that the unsaturated fatty acids 18:2 or 20:4 have a stronger impact on the synthesis of phospholipid molecular species than the saturated fatty acids 16:0 or 18:0 have. Thus 20:4,n-6 and 18:2,n-6 are able to direct available [14C]16:0 or [14C]18:0 to the sn-1 position. 16:0 and 18:0 are not in the same way able to direct [14C]18:2,n-6 to the synthesis of 16:0-18:2 or 18:0-18:2 at the expense of other 14C-labelled molecular species. | lld:pubmed |
| pubmed-article:8011678 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8011678 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8011678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8011678 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8011678 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:8011678 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:8011678 | pubmed:author | pubmed-author:Christopherse... | lld:pubmed |
| pubmed-article:8011678 | pubmed:author | pubmed-author:WoldsethBB | lld:pubmed |
| pubmed-article:8011678 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8011678 | pubmed:day | 23 | lld:pubmed |
| pubmed-article:8011678 | pubmed:volume | 1213 | lld:pubmed |
| pubmed-article:8011678 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8011678 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8011678 | pubmed:pagination | 39-45 | lld:pubmed |
| pubmed-article:8011678 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:meshHeading | pubmed-meshheading:8011678-... | lld:pubmed |
| pubmed-article:8011678 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8011678 | pubmed:articleTitle | Biosynthesis of phospholipid molecular species in isolated liver cells studied by combining fatty acid substrates esterified in the sn-1 and sn-2 positions. | lld:pubmed |
| pubmed-article:8011678 | pubmed:affiliation | Institute of Clinical Biochemistry, University of Oslo, Rikshospitalet, Norway. | lld:pubmed |
| pubmed-article:8011678 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8011678 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
