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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1994-7-28
|
| pubmed:abstractText |
An inclined sedimentation chamber and a modified 250-ml Erlenmeyer flask have been used as separation devices for perfusion fermentations with hybridoma cells. The maximum cell density is increased 2-16-fold compared to batch fermentations when the separation units are used. When the sedimentation chamber is used, IgG is continuously produced and the daily production is increased by a factor 3.7 compared to batch fermentation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0168-6445
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
89-91
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8011363-Animals,
pubmed-meshheading:8011363-Antibodies, Monoclonal,
pubmed-meshheading:8011363-Cell Count,
pubmed-meshheading:8011363-Fermentation,
pubmed-meshheading:8011363-Hybridomas,
pubmed-meshheading:8011363-Immunoglobulin G,
pubmed-meshheading:8011363-Mice,
pubmed-meshheading:8011363-Perfusion
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Perfusion systems for hybridoma cells based on sedimentation in chambers and Erlenmeyer flasks.
|
| pubmed:affiliation |
Department of Biotechnology, Technical University of Denmark, Lyngby.
|
| pubmed:publicationType |
Journal Article
|