Linked Life Data

8008455

Source:http://linkedlifedata.com/resource/pubmed/id/8008455

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1994-7-18
pubmed:abstractText
The question of whether the known immunosuppressive effects of Babesia microti may disrupt the development of acquired resistance to its tick vector, Ixodes trianguliceps, in natural rodent hosts (Clethrionomys glareolus), and thus enhance the disease transmission potential, is addressed experimentally. The results show for the first time that natural hosts can acquire resistance to ticks; that this acquired resistance is manifested chiefly by a strongly density-dependent reduction in the percentage of attached larvae that engorge; that the density dependence is quantitatively similar whether the host receives occasional large tick challenges or frequent low infestations; but that infection with B. microti does not disrupt this pattern of acquired resistance. Of two important natural host species, Apodemus sylvaticus can support repeated infestations of I. trianguliceps, but is a poor host to B. microti, while C. glareolus develops acquired resistance to the tick vector, but supports much higher-level, longer-lasting B. microti infections.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0031-1820
pubmed:author
pubmed:issnType
Print
pubmed:volume
108 ( Pt 4)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
413-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Density-dependent acquired resistance to ticks in natural hosts, independent of concurrent infection with Babesia microti.
pubmed:affiliation
Department of Zoology, University of Oxford.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't