Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1994-7-20
pubmed:abstractText
The CS31A antigen was first described for septicemic and enterotoxigenic bovine E. coli strains. In our study, of 597 human Escherichia coli strains isolated from diarrheagenic stools of hospitalized patients, 30 (5%) hybridized with the CS31A DNA probe. These CS31A-positive E. coli strains diffusely adhered to Caco-2 and/or HEp-2 cells and produced a major surface protein of either 30 or 30.5 kDa according to the strain. These proteins were antigenically related to the two forms of the CS31A antigen, namely, CS31A-L and CS31A-H. Genes encoding CS31A were located on 140-kb conjugative R plasmids. E. coli transconjugants expressed major surface proteins similar to those of the wild-type strains and adhered to Caco-2 and/or HEp-2 cells. An association of CS31A and another adhesive factor of the Dr family was found in 70% of wild-type strains, since 21 strains hybridized with the diffuse adhesion DNA probe corresponding to the accessory gene (daaC) of the F1845 adhesin. Comparison of the restriction patterns of the 140-kb R plasmids of the CS31A-positive E. coli strains showed these plasmids to be similar. Hybridization experiments indicated that the genes encoding CS31A and resistance to penicillin were located together on either of two 20- or 27-kb EcoRI restriction fragments in four E. coli strains. We reported a similar linkage between these genes in Klebsiella pneumoniae strains which produced CF29K, a CS31A-like antigen. These results suggest a horizontal transfer between E. coli and K. pneumoniae strains.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-1100526, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-1106293, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-1195397, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-1682255, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-1686628, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-1938963, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2180823, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2227363, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2565291, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2568985, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2668111, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2893773, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2899553, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2962945, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-2973271, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-3075501, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-3259120, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-327080, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-3529604, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-388356, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-388439, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-5432063, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-6296043, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-6657780, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-7009583, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-8095911, http://linkedlifedata.com/resource/pubmed/commentcorrection/8005677-8370727
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0019-9567
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2865-73
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Self-transmissible R plasmids encoding CS31A among human Escherichia coli strains isolated from diarrheal stools.
pubmed:affiliation
Laboratoire de Bactériologie, Faculté de Pharmacie, Clermont-Ferrand, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't